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Council's Research Work

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2014 - 20193

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Author: search.filters.author.Shah, RajeshStart date: 2000

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    Preparation and standardisation of Plasmodium falciparum nosode
    (2019) Shah, Rajesh
    Background: Malaria officinalis, a Homoeopathic preparation used against malaria, was prepared from decomposed vegetable matter from a marshy area by G. W. Bowen in 1862. No scientific published material is available on the source of any malaria related nosode. There is a need to develop the new nosode using the organisms. The author has developed the nosode from Plasmodium falciparum parasites, and the detailed method of preparation is described in this manuscript. Objective: Preparation and standardisation of Homoeopathic nosode prepared from P. falciparum parasites, which could be explored for further research and therapeutic efficacy. Materials and Methods: The most widely cultivated strain of malaria parasite P. falciparum was collected from Indian Institute of Technology B (Mumbai). This parasite was triturated with nine parts of Saccharum lactis powder to achieve 1X potency. One part of 1X potency and nine parts of Saccharum lactis powder were taken to make subsequent 2X potency. Likewise, potencies till 6X were prepared by trituration method, prescribed in Homoeopathy pharmacopeia of India (HPI). Results: Nosode from P. falciparum strain was prepared by trituration method as prescribed in HPI and standardised for future research and clinical exploration. Conclusion: The nosode sourced from P. falciparum parasites will be one such addition, which will call for further exploration for its effect against malaria (and other diseases) as a prophylactic and therapeutic measure.
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    Scientific method of preparing homoeopathic nosodes
    (2014) Shah, Rajesh
    Introduction: Nosodes are homoeopathic preparations sourced from biological materials such as diseased tissues, organisms, cultures (bacteria, fungi, and viruses), or parasites, or from decomposed products from humans or animals. More than forty?five major nosodes have been in use since 1830 but no clear guidelines regarding their preparation are available. Objective: To standardize the method of preparation of nosodes using modern technology and lay down clear guidelines for the same. Materials and Methods: Biological material identification such as culture of organism, separation of required pure fraction, quantification, standardization, dilutions, potentisation method, and safe use of nosodes were documented in a systematic way. Result: HIV, HCV and Mycobacterium tuberculosis nosodes were prepared using the modified method described in this article. Conclusion: The improved method of nosode preparation can pave way for laying clear guidelines for preparation of nosodes in homoeopathic pharmacopeias.