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Investigation of molecular footprints in ultra-high diluted homoeopathic solutions of Arnica montana Arnica montana andand Rhus toxicodendron through combined infrared and impedance spectroscopy
(CCRH, 2026) Kundu, Sharbadeb; Dash, Usha Rani; Chaudhuri, Chirasree Roy
Background:Background: The study of ultra-high diluted (UHD) solutions is a compelling and controversial domain in modern science. Despite numerous investigations and hypotheses, there is a lack of rigorous, reproducible empirical evidence supporting the existence of molecular footprints beyond the Avogadro's limit. Objective:Objective: This study conducted a detailed investigation of the molecular and electrical properties, focusing on hydrogen bonding and impedance to understand the fundamental nature of UHD solutions. Materials and methods:Materials and methods: Combined impedance and infrared spectroscopic investigations were performed to probe the structural behaviour of relevant water networks at the molecular level of UHD alcoholic extract of Arnica montana (AM) and Rhus toxicodendron (RT). Results:Results: At higher potencies (200C and 1M) of both AM and RT, an interesting correlation was observed between impedance and spectral characteristics. An increase in impedance was observed with potencies for both AM (93.9%) and RT (49%), which was attributed to changes in the hydrogen bonding network and molecular reorganisation during potentisation. This correlates with the Mid-IR spectra, showing increased hydrogen bond length and potential weakening of inter-molecular hydrogen bonds with increasing potency. Also, Far-IR spectra indicate a contrast in the system's enthalpic gain with increased potencies for both AM (29.8%) and RT (65.2%). Conclusion:Conclusion: Distinct variations in spectral and electrical parameters have been observed for AM and RT due to potentisation, suggesting that these solutions retain structural and molecular traits despite extreme dilutions. This notion may revisit traditional homoeopathic treatment approaches by addressing conflicting paradigms regarding the presence of molecular footprints in UHD solutions.
Fundamental research principles in Homoeopathy
(CCRH, 2026) Shekhar, Himanshu; Aphale, Parth; Dokania, Shashank
Bridging the gap in women's healthcare
(CCRH, 2026) Kaushik, Subhash
Research Highlights
(CCRH, 2026) Gupta, Meenu; Shanker, Sunaina
Screening of antiurolithiatic activity of different formulations of homoeopathic medicines using calcium oxalate crystallisation assay
(CCRH, 2026) G, Loganathan; T, Satesh
Background: Homoeopathic medicines such as Aerva lanata, Hydrangea arborescens, Berberis vulgaris, and Sarsaparilla are commonly used to treat kidney stones. Scientific research is needed to understand their effects on calcium oxalate crystallisation, a key factor in urolithiasis. Objective: The study evaluated the in vitro effects of Aerva Lanata, Hydrangea Arborescens, Berberis Vulgaris, and Sarsaparilla in Q, 6C, and 30C potencies on calcium oxalate crystallisation. It aimed to identify which potency had the strongest inhibitory effect compared to Ethanol (90%). Methods: Calcium oxalate (CaOx) crystals were synthesised by mixing calcium chloride and sodium oxalate, then cooled to 37 °C to achieve a concentration of 0.8 mg/mL in Tris buffer (pH 6.5). Homoeopathic remedies (Aerva lanata, Berberis vulgaris, Hydrangea arborescens, and Sarsaparilla in Q, 6 C, and 30 C potencies) and ethanol (90%) were tested at concentrations of 1000 to 10 μg/ml. After 24 hours at 37 °C, turbidity was measured, and crystal morphology was examined under an inverted light microscope. Results: Aerva lanata Q, Aerva lanata 6C, and Berberis vulgaris Q significantly inhibited stone formation compared to the ethanol control group, with Aerva Lanata Q demonstrating the most pronounced effect. Light microscopy revealed diverse crystal morphologies, underscoring the role of Calcium Oxalate crystals in kidney stone formation. Conclusion: Aerva lanata and Berberis vulgaris show potential in inhibiting calcium oxalate crystal formation, suggesting a role in preventing urolithiasis.