Study of Heart Rate In Swiss Albino Mice Treated With Potentised Sodium Pentobarbitone During Anaesthesia

Abstract

With an object to demonstrate the action of solvents potentised beyond the limit of existence of the medicinal material in them, head rate was monitored as a function of time in twenty Swiss Albino Mice under anaesthesia. It was observed that the normalised heart rate decreased to 0.818+ 0.0796 during anaesthesia in ten animals treated with distilled water. The anaesthised animals treated with 15th potency of sodium pentobarbitone showed an initial increase in the heart rate with subsequent reduction to 0.936+ 0.086, significantly different from that of controls.