Indian Journal of Research in Homoeopathy
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Item Effectiveness of individualised Homoeopathy in hypertrophied adenoids in pediatric population: a single-arm, prospective pilot study(Central Council for Research in Homoeopathy, 2025) Ussi, Shereena; Ramanan, Vinitha EdavattathBackground: Adenoid hypertrophy is the most common cause of upper airway obstruction in children. Objective: The primary objective was to determine the reduction in hypertrophied adenoids in children after homoeopathic treatment, using nasal endoscopic assessment. The secondary objectives were to identify the changes in symptoms of hypertrophied adenoids in children after administration of homoeopathic medicines using “Four-point clinical rating scale for adenoidal symptoms (FPCR)” and to nd out the utility of homoeopathic medicines in reducing the frequency of upper respiratory tract infections (URTI) in children with hypertrophied adenoids. Materials and methods: Thirty children between 3–14 years of age, with signs and symptoms of hypertrophied adenoid were screened from the outpatient department of National Homoeopathy Research Institute in Mental Health, Kerala, India, in 2019. It was a single-arm-prospective study. The treatment effect was analysed by evaluating the endoscopic grading of hypertrophied adenoids, reducing the frequency of URTI, and the FPCR scale for adenoidal symptoms. Results: Nasal endoscopy at the end of one year of homoeopathic treatment revealed no further increase in size of the adenoids in 19 cases, whereas in 11 cases the size increased. There was a statistically signi cant reduction in the FPCR scale (z D 4.724, p < 0.001). The frequency of URTI reduced from six episodes in six months to less than four episodes in twelve months. Conclusion: The study shows a probable role of homoeopathic medicines in reducing the size of adenoid hypertrophy and reducing the frequency of upper respiratory tract infections in children.Item Mixed hearing loss with CSOM managed with individualised homoeopathic treatment(Central Council for Research in Homoeopathy, 2025) Prince KumarIntroduction: Any stage of life might see the development of hearing loss (HL). One or both ears may be affected, and the onset may occur suddenly or gradually. Numerous factors, such as trauma, illness, genetic disorders, age, or prolonged exposure to noise, can cause HL. One or more auditory system areas may have pathological alterations as a result of the changes. The majority of adult HL is permanent or gradually progresses; however, some may be momentary or amenable to treatment with medication or surgery. Case Summary: A 17-yearold male adolescent was treated with homoeopathic medicine in an obstinate case of mixed HL with persistent otorrhoea. An individualised homoeopathic medicine, Calcarea sulph., was prescribed after thorough case taking, which led to a significant reduction of subjective and objective symptoms over a period of ten months. The pure tone audiometric (PTA) test was done before and after the homoeopathic treatment, which showed gradual improvement in hearing. This case shows that individualised homoeopathic medicine selected based on the totality of symptom can have favourable results in the treatment of mixed HL with evidence of PTA. The evaluation of the causal attribution of homoeopathic medicine was conducted using the Modified Naranjo Criteria for Homoeopathy. This assessment resulted in a score of +9, indicating a definitive causal relationship between the administered medicine and the observed outcome. The findings suggest that when a homoeopathic remedy is appropriately selected, it can be effective in treating HL.Item Immunoglobulin E modulatory effect of individualised Homoeopathy in a child suffering from immunological, chronic spontaneous urticaria(Central Council for Research in Homoeopathy, 2025) Sonny, Ranjit; Parui, PatranuIntroduction: Urticaria is one of several immune-mediated diseases. It is very troublesome and hampers the quality of life significantly. Chronic spontaneous urticaria (CSU) is associated with red, oedematous, erythematous, raised and itchy wheals with or without angioedema. A serological marker such as immunoglobulin E (IgE) is raised in urticaria, which is one of the diagnostic criteria of urticaria. The successful treatment lies in the fact of controlling or immunomodulating the IgE level. As per available data, Homoeopathy is very effective for the management of urticaria by bringing down the serum IgE level within normal limits. Case Summary: A 10-year-old female child visited the outpatient department with the complaint of urticaria along with increased serum IgE level. In the first visit, all the symptoms, objective and subjective, were collected, followed by framing of the totality of symptoms and repertorisation. The anti-allergic medication before the visit was gradually tapered off. The MONARCH score of +7 proved the causal attribution between the medicine and the outcome in the patient. The eruption of urticarial rashes eventually stopped, and the IgE level was restored to normal range. This case study reveals a positive role of homoeopathic treatment in immune-mediated diseases such as urticaria.Item Effect of individualised homoeopathic intervention in dyslipidaemia(Central Council for Research in Homoeopathy, 2025) Varanasi, Roja; Bhalerao, Rupali; Raveendar ChBackground: Dyslipidaemia, the derangement of one or many of the lipoproteins is a major cause of cardiovascular events, causing 2.6 million deaths per year globally. Objectives: This study evaluated the efficacy of individualised homoeopathic medicines with lifestyle modification in the management of dyslipidaemia. Materials and Methods: This multicentric, open-label, randomised controlled exploratory trial was conducted at seven study sites under the Central Council for Research in Homoeopathy. Participants fulfilling the eligibility criteria were enrolled. The primary outcome was to evaluate changes in Low-Density Lipoprotein cholesterol at months 3 and 6. Secondary outcomes were to evaluate changes in total cholesterol, triglyceride, and high-density lipoprotein at months 3 and 6. Results: All pre-determined study outcomes followed the intention-to-treat approach. 217 patients (Individualised Homoeopathy (IH) along with lifestyle modification (IH plus therapeutic lifestyle changes [TLC]) n = 107; Placebo along with TLC (n = 110) were enrolled and analysed. Independent t-test at month 6 showed a statistically significant reduction in LDL (mean difference ± standard error: 7.03 ± 3.3; 95% confidence interval = 0.5–13.5; p = 0.03) favouring IH over placebo. Improvement in secondary outcomes; reduction in total cholesterol (p > 0.05) and triglycerides (p > 0.05) was greater in the IH group but was statistically insignificant (p > 0.05). Associated symptoms such as rheumatological and neurological complaints also improved in the IH group. Frequently prescribed medicines were Lycopodium, Sulphur, and Calcarea carbonica. Conclusion: IH along with lifestyle modification was found to play a potential role in reducing the LDL cholesterol and in the management of dyslipidaemia. Further blinded studies in different settings and long-term follow-up are warranted.