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Indian Journal of Research in Homoeopathy

Permanent URI for this collectionhttps://aoh.ccrhlibrary.in/handle/123456789/38

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Start date: 2025Subject: search.filters.subject.Homoeopathy

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    Fundamental research principles in Homoeopathy
    (CCRH, 2026) Shekhar, Himanshu; Aphale, Parth; Dokania, Shashank
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    Bridging the gap in women's healthcare
    (CCRH, 2026) Kaushik, Subhash
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    Research Highlights
    (CCRH, 2026) Gupta, Meenu; Shanker, Sunaina
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    Screening of antiurolithiatic activity of different formulations of homoeopathic medicines using calcium oxalate crystallisation assay
    (CCRH, 2026) G, Loganathan; T, Satesh
    Background: Homoeopathic medicines such as Aerva lanata, Hydrangea arborescens, Berberis vulgaris, and Sarsaparilla are commonly used to treat kidney stones. Scientific research is needed to understand their effects on calcium oxalate crystallisation, a key factor in urolithiasis. Objective: The study evaluated the in vitro effects of Aerva Lanata, Hydrangea Arborescens, Berberis Vulgaris, and Sarsaparilla in Q, 6C, and 30C potencies on calcium oxalate crystallisation. It aimed to identify which potency had the strongest inhibitory effect compared to Ethanol (90%). Methods: Calcium oxalate (CaOx) crystals were synthesised by mixing calcium chloride and sodium oxalate, then cooled to 37 °C to achieve a concentration of 0.8 mg/mL in Tris buffer (pH 6.5). Homoeopathic remedies (Aerva lanata, Berberis vulgaris, Hydrangea arborescens, and Sarsaparilla in Q, 6 C, and 30 C potencies) and ethanol (90%) were tested at concentrations of 1000 to 10 μg/ml. After 24 hours at 37 °C, turbidity was measured, and crystal morphology was examined under an inverted light microscope. Results: Aerva lanata Q, Aerva lanata 6C, and Berberis vulgaris Q significantly inhibited stone formation compared to the ethanol control group, with Aerva Lanata Q demonstrating the most pronounced effect. Light microscopy revealed diverse crystal morphologies, underscoring the role of Calcium Oxalate crystals in kidney stone formation. Conclusion: Aerva lanata and Berberis vulgaris show potential in inhibiting calcium oxalate crystal formation, suggesting a role in preventing urolithiasis.
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    Homoeopathic management of mania with psychotic symptoms
    (CCRH, 2026) Bhuvaneswari, R; V, Sakthivel
    IntroductionIntroduction: Manic episode (ICD-F30.2) is typically characterised by distinct period of abnormally and persistently elevated, expansive, or irritable mood, along with abnormally and persistently increased goal-directed activity or energy, lasting at least 1 week and causing significant disruption in occupational and social functioning. The lifetime risk of experiencing manic episodes is approximately 0.8–1%. These episodes typically recur in three to four-month cycles. This case report aims to highlight significance of individualised homoeopathic treatment in managing mania with psychotic symptoms over a 41-month period without relapse, and without the use of conventional medication. Case Summary:Case Summary: An 18-year-old female was brought by her parents to the psychiatry outpatient department on August 1, 2022 with complaints of agitation, anger, and irritability, reduced sleep, abusive language, suspiciousness, and pressured speech. She believed her parents were hacking her phone and harming her since 12 days. A consultant psychiatrist diagnosed her with mania with psychotic symptoms, and the severity was measured using the YMRS and BPRS scales. Lachesis 200C was prescribed, followed by a single dose ofCarcinosinum 200C as constitutional medicine. The YMRS score dropped from 48 to 0 within a week, and the BPRS score from 70 to 0 in three months, with no homoeopathic aggravation noted. MONARCH, score 7, suggests a causal attribution to disease improvement. Thus, indicating a correlation between medication and outcome. There was a significant improvement change within a week. Homoeopathic medicines selected based on individualisation are effective in the treatment of mania with psychotic symptoms.
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    Non-invasive treatment for indolent chronic venous ulcer using individualised Homoeopathy
    (CCRH, 2026) Ramanan, Vinitha Edavattath; KP, Geethu
    Background: Venous ulcers account for 60–70% of all leg ulcers. They are irregular ulcers with sloping edges mainly seen above the medial malleolus associated with oedema, lipodermatosclerosis and hemosiderosis. Conventional medicine mentions chronic venous ulcers as a surgical disease. It usually results in further co-morbidities and reduces the patient’s quality of life. Homoeopathic literature describes many medicines for the treatment of varicose ulcers. This case series demonstrates the role of homoeopathic treatment in the complete healing of venous ulcers non-invasively. Case Summary: This is a case series of five patients suffering from chronic venous ulcers resistant to conventional external medications who visited the OPD of National Homoeopathy Research Institute in Mental Health Kottayam, Kerala, India during 2022–23. All the cases received individualised homoeopathic medicines internally. Conclusion: The ulcers healed completely within an average two-month period in all five cases, evidenced by images taken before and after treatment. The MONARCH score was calculated as +9/13, +8/13, +8/13, +8/13, and +8/13 for the five cases, indicating a definitive causal relationship between the medicine prescribed and the treatment outcome in the first case and probable relationship in the rest of the cases. Sulphur was prescribed in three cases, Pulsatilla and Arsenicum album in the rest of the cases. This case series suggests individualised Homoeopathy can help to treat venous ulcers.
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    Efficacy of individualised homoeopathic medicines as an adjunct to conventional iron and folic-acid supplementation in ironto conventional iron and folic-acid supplementation in iron deficiency anaemia among reproductive-aged women
    (CCRH, 2026) Hazra, Avidipta; Sarkar, Tanmay; Das, Debarsi
    Background: Iron deficiency anaemia (IDA) is a major public health concern affecting women of reproductive age globally. If left untreated, it can cause various health issues including fatigue, shortness of breath, abnormal heart rhythms, chest pain, and complications during pregnancy. Objectives:Objectives: To evaluate the efficacy of individualised homoeopathic medicines (IHMs) with iron and folic acid supplement (IFS) in treatment of iron deficiency among reproductive-aged women, in comparison with placebos with IFS. Methods:Methods: Single-blind, randomised, placebo-controlled clinical trial was conducted over total six months at the outpatient-department, of which participants received interventions and outcome assessments for three months. Reproductive women (15–49 years) with IDA were included based on haemoglobin (Hb) level ≤ 11.9 mg/dl to ≥ 7.1 mg/dl with serum ferritin <15 >μ g/l; randomised to receive either IHMs with IFS (IHMs-IFS, n = 30) or identical-looking placebos with IFS (placebo-IFS, n = 30) for 3 months. The outcomes included haemoglobin, Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH), serum ferritin (SF) levels measured at baseline and after three-months of intervention. Results:Results: Of 110 screened participants, 60 were included after their consent and intervened; entered into intention-to-treat analysis. Inter-group differences shown Hb, MCV, SF values were statistically significant with medium effect size. Intra-group differences showed in Hb (IHMs-IFS: p < 0.001; placebos-IFS: p < 0.01), MCV (IHMs-IFS: p < 0.001; placebos-IFS: p < 0.01), MCH (IHMs-IFS: p < 0.001, placebos-IFS: p < 0.01), SF (IHMs-IFS:p < 0.001; placebos-IFS: p < 0.001) significant increases in both groups. Conclusion:Conclusion: Significant improvement was observed, within and between the groups. However, the magnitude of improvement was slightly greater in IHMs-IFS group compared with placebo-IFS group, indicated by larger mean changes and medium effect sizes, favouring the adjunct benefits of IHMs in management of IDA among reproductive-age women. Multi-centric, double-blinded, large- sampled studies are warranted to confirm these findings.
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    Physicochemical, pharmacognostic standardisation and phytochemical analyses of the homoeopathic drug Justicia adhatoda
    (Central Council for Research in Homoeopathy, 2025) Biswas, Bibaswan; Patel, Satish; Verma, Digvijay; Maity, Satyajit
    Background: Justicia adhatoda (J. adhatoda), also well known as Vasaka in India is a medicinal plant chiefly used to treat respiratory ailments in traditional and alternative medical systems. Objective: This study aimed to establish the physicochemical, pharmacognostic, and phytochemical standardisation parameters of the drug. The study involved the measurement of physicochemical parameters and chemical profiling of the raw drug. The chemical characteristics of the in-house mother tincture (prepared from in-house raw drug) and commercial mother tinctures available in India were also evaluated to assess the quality of commercially available mother tinctures. Materials and Methods: The present study included pharmacognostic parameters like macroscopic, microscopic, powder studies and physicochemical parameters involving foreign matter, loss on drying, extractive values in different solvents, ash value measurements, total alkaloid content, total fixed oil and total volatile oil of the raw drug. This study also included measurement of various mother tincture parameters, such as organoleptic characteristics, specific gravity, pH, total solids, UV–Vis spectrum, high performance thin-layer chromatography (HPTLC), phytochemical screening, total alkaloid content, and chemical profiling of commercial and in-house mother tinctures to assess their comparative quality. Results: The macroscopic and microscopic studies revealed the pharmacognostic characteristics of the leaves. Low ash values indicated low metal contents. The chemical profiling and analysis indicated the presence of the same alkaloid in the raw drug and in the mother tinctures. The drug also contained several phytochemicals. Conclusion: The present study provides pharmacopoeial standards for J. adhatoda.
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    Homoeopathic intervention in dual autoimmune disorders: A case report on management of vitiligo and hashimoto thyroiditis
    (Central Council for Research in Homoeopathy, 2025) Saklani, Nitin Kumar
    Background: Vitiligo and Hashimoto Thyroiditis often occur as chronic autoimmune disorders that require careful evaluation and individualised management. This case study examines the usefulness of homoeopathic interventions in addressing the complexities of Vitiligo and Hashimoto Thyroiditis through evidence-based methodologies. Case Summary: A 57-year-old woman initially sought medical attention for a noticeable whitish discolouration on the left side of her lips. Subsequent evaluations unveiled the presence of hypothyroidism, marked by elevated Anti-TPO levels, exposing the dual autoimmune nature of her condition. The patient’s concerns centered on the aesthetic impact of vitiligo on her lips and the broader health implications of Hashimoto’s Thyroiditis. The coexistence of vitiligo and Hashimoto’s thyroiditis required simultaneous evaluation of both dermatological and thyroid-related findings. The patient underwent homoeopathic treatment at the outpatient department of the Regional Research Institute for Homoeopathy, Shimla. Following the intervention, recovery from the signs and symptoms of both vitiligo and Hashimoto’s Thyroiditis was observed. Photographic evidence and serological investigations, including Serum TSH and anti-TPO, demonstrated significant improvement in the conditions. This evidence-based case report highlights the potential positive role of Homoeopathy in the management of complex dual autoimmune conditions, providing insights into the successful recovery of the patient both clinically and serologically.
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    Indian Standard for Globules used in Homoeopathy
    (Central Council for Research in Homoeopathy, 2025) Vivekanand, Kumar; Katarmal, Daisy; Saxena, Indra Gaurav; Taneja, Divya; Dixit, Shrishti; Manchanda, Raj Kumar
    This article aims to describe and critically examine the Indian Standard (IS 18947:2024) for globules used in Homoeopathy, outlining the technical specifications, testing methods, and significance for pharmaceutical quality assurance. The implications of the standard for manufacturers, quality control laboratories, consumers and regulatory bodies engaged in the production and evaluation of homoeopathic drugs are highlighted by presenting a consolidated view of the standard’s scope and applications. This discussion underscores the continued importance of systematic standardization in ensuring the safety, consistency, and global credibility of homoeopathic medicinal products produced in India.