Indian Journal of Research in Homoeopathy
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Item Celebrating World Homoeopathy Day with a homoeopathic symposium on empowering research, enhancing proficiency(Central Council for Research in Homoeopathy, 2024) Kondle, Babita Rani; Taneja, Divya; Mittal, Renu; Kaushik, SubhashThe Honourable President of India, Smt. Droupadi Murmu inaugurated the scientific convention ‘Empowering Research Enhancing Proficiency: A Homoeopathic Symposium’ on 10th and 11th April 2024 at Yashobhoomi (India International Convention and Expo Centre), New Delhi, India. The convention which was jointly organised by the Central Council for Research in Homoeopathy, National Commission for Homoeopathy and National Institute of Homoeopathy under the aegis of the Ministry of Ayush, Government of India to commemorate the 269th birth anniversary of Dr. Christian Friedrich Samuel Hahnemann. There were a total of 17 sessions which included five panel discussions. The convention was attended by more than 6000 delegatesItem The role of Hepar sulphuris calcareum in a case of periorbital cellulitis(Central Council for Research in Homoeopathy, 2024) Desai, Rushikesh Ramesh; Choudhary, Mahesh MIntroduction: Periorbital cellulitis is an infection of the soft tissues around the eye anterior to the orbital septum. This condition is very commonly found in the paediatric population but due to certain comorbidities such as diabetes mellitus or immune-compromised conditions, it can be seen in the adult population also. The condition may prove devastating to the eye, causing complete loss of vision or may become life-threatening if the infection spreads to orbits and involves cavernous sinuses in the brain. Case Summary: A 50-year-old diabetic male patient complained of red and lustrous swelling around his right eye, sticky discharge from the eye and increased lachrymation. The swelling was preceded by furuncle on the right zygomatic region of the face 5–6 days before the involvement of the eye. He was diagnosed with periorbital cellulitis and was asked by a local practitioner to go with the course of antibiotics, but the patient was reluctant to take allopathic medication and hence approached for homoeopathic medication. After taking details of his acute episode, Hep. sul. 30C was prescribed 4 hourly. Within 24 h, there was a remarkable reduction seen in the periorbital and ocular congestion and oedema. This case depicts the rapid, gentle and permanent restoration of health if the similimum is accurate.Item An in vitro comparative assessment of antidiabetic efficacy(Central Council for Research in Homoeopathy, 2024) Mary Adharshna S.P.; Arul, VettrivelBackground: Homoeopathic mother tinctures are gaining attention for managing diabetes by inhibiting key enzymes in glucose metabolism. Objective: This study aimed to compare popular homoeopathic mother tinctures Abroma augusta Q (AAQ), Cephalandra indica Q (CIQ), Gymnema sylvestre Q (GSQ), Momordica charantia Q (MCQ) and Syzygium jambolanum Q (SJQ) with Metformin (MET) in inhibiting diabetes associated α-amylase and α-glucosidase enzymes. Methods: Mother tinctures AAQ, CIQ, GSQ, MCQ, SJQ and MET of concentrations 10 μL/mL, 50 μL/mL, 100 μL/mL, 250 μL/mL, and 500 μL/mL were assessed through α-amylase and α-glucosidase inhibitory assay. Results: All mother tinctures show significant inhibitory action at p < 0.01. AAQ and GSQ exhibited potent inhibition of both enzymes, with inhibitory percentages ranging from 70.41% (500 μL/mL) to 58.98% (10 μL/mL) for α-amylase and 68% (500 μL/mL) to 43.72% (10 μL/mL) for α-glucosidase and 73.98% (500 μL/mL) to 63.66% (10 μL/mL) for α-amylase and 65.31% (500 μL/mL) to 25.99% (10 μL/mL) for α-glucosidase, respectively. AAQ has an IC50 value of 107.9 μL/mL (α-amylase) and 43.87 μL/mL (α-glucosidase) which makes it evidently, a potent antidiabetic mother tincture. Conclusion: AAQ and GSQ demonstrated significant inhibition of diabetes associated enzymes when compared with METItem Lateral venous ulcer treated with Homoeopathy using a miasmatic approach(Central Council for Research in Homoeopathy, 2024) Moorthi, Karunakara; Reshma, P.Introduction: Loss of all or a portion of the dermis, as well as the epidermis, causes an open sore known as an ulcer. Venous leg ulcers are late signs of venous hypertension and chronic venous insufficiency. Long-term ulcers are difficult to heal and lastly opted for skin grafting and surgery conventionally. This case report provides insight into the treatment of venous ulcer with homoeopathy using the miasmatic approach and helps to provide evidence for further research in this area. Case Summary: A 61-year-old female presented with ulceration near the lateral malleolus of her left leg for the past 6 years. The non-healing ulcer was successfully treated with homoeopathic treatment within 1 year. After case taking, Syphilinum 200C was prescribed considering the miasmatic expression, resulting in symptomatic improvement and Calendula Q externally for an initial 30 days as supportive care followed by Sulphur 200C toward the end of treatment. Homoeopathic medicines led to a remarkable improvement, it was measured using the leg ulcer measurement tool along with photographic evidence and Modified Naranjo Criteria for Homoeopathy. Conclusion: The result was encouraging, exclusively with Homoeopathy medicine; yet, for stronger evidence, more extensive, rigorous research projects are required.Item Homoeopathy in the treatment of tinea cruris and tinea corporis(Central Council for Research in Homoeopathy, 2024) Mittal, Renu; Prusty, Akshaya Kumar; Shivadikar, Ashish; Taneja, Divya; Kumari, Noopur; Kaushik, SubhashBackground: Dermatophytosis is a fungal infection affecting keratinised tissues such as the epidermis, hairs and nails. It is particularly prevalent in tropical regions due to favourable conditions for fungal growth, such as warmth and humidity. Dermatophytes metabolise keratin leading to various pathological clinical presentations, such as tinea pedis, tinea corporis and tinea cruris. Case reports, case series and studies published on treatment of tinea corporis add to the evidence-based effectiveness of Homoeopathy in treatment of the condition. Objective: The objective of the study was to assess the therapeutic efficacy of individualised homoeopathic medicines in the clinical management of cases presented with tinea cruris and tinea corporis. Methods: The present case series includes 26 cases of dermatophytosis. KOH mount test was used as the diagnostic tool for confirming tinea infection. Clinical Cure, Skindex-16 and Global Evaluation Response were the main outcome assessment tools. The causal relationship between intervention and outcome was assessed through MONARCH criteria. Results: Out of 26 cases, nine cases (34%) experienced complete disappearance of lesions, 14 cases (53.8%) showed symptomatic improvement and progression of lesions was seen in three cases (11.5%). The collated data of these 26 cases showed a significant reduction in mean Clinical Cure Composite Score (pruritus, erythema and scaling) (p = 0.000) and Skindex-16 composite scores (p = 0.00) were observed. Conclusion: This series provides evidence supporting the usefulness of Homoeopathy treatments for dermatophytosis, particularly tinea cruris and tinea corporis. Employing clinical assessments, standardised evaluation metrics and photographic documentation ensures a thorough and objective evaluation of treatment usefulness and patients’ quality of life.Item When little beings are celebrated with gentle, healing hands(Central Council for Research in Homoeopathy, 2024) Kaushik, SubhashItem Role of homoeopathic medicine in the management of psoriasis(Central Council for Research in Homoeopathy, 2024) Chaurasiya, Priya Bablesh; Chaphekar, Priya Gauri A.; Ingale, Sailee V.Introduction: Psoriasis is a common chronic, recurrent, immune-mediated disease, where plaque-type psoriasis and psoriatic arthritis show 90 % and 7% prevalence, respectively. It is a cosmetically expressed condition that impacts the individual and the family, thus affecting quality of life. It impacts the physical, emotional and psychosocial well-being of the sick individual. It accounts for up to 3% of the World’s population. Although this condition is not life-threatening, it is challenging to treat due to the lack of established causative factors. Conventional medicine offers long-term treatment with a short-term benefit to patients with psoriasis, resulting in discontinued treatment by the patients. Case Summary: A 46-year-old male presenting with psoriasis was treated with homoeopathic similimum Arsenicum album and intercurrent remedy X-ray. The periodical assessment of the treatment was done before and after the treatment and using the PASI score to ascertain the prognosis. As psoriasis is a chronic and recurrent condition, the severity index shows changes over 11 months with slight aggravation in the lesion at the beginning of winter. The Modified Naranjo Criteria for Homoeopathy (MONARCH) tool was used and a score of +9 suggested a possible causal attribution between the intervention and outcome. The above assessment was strengthened with pictographic evidence. This case report reinforces the role of Homoeopathy in the management of psoriasis using a homoeopathic similimum and an intercurrent remedy.Item Efficacy of Ferrum metallicum 30C in restoring menstrual cycle in polycystic ovarian syndrome patients(Central Council for Research in Homoeopathy, 2024) Jerin, J. P.; Nayak, Chaturbhuja; Karthikeyan, D.; Rajagopalan, MaanasaBackground: Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder affecting women of reproductive age, with the prevalent clinical symptom of irregular menstruation. Objective: This trial assessed the efficacy of Ferr. met. 30C in restoring the menstrual cycle among PCOS patients. Methods: A randomised, placebo-controlled, single-blind trial was conducted at outpatient departments of Sri Sai Ram Homoeopathy Medical College and Research Centre, Chennai. Patients were randomly allotted to the experimental (Group I - Ferr. met. 30C) and control (Group II - Placebo) groups. Quality of life of patients in both groups was assessed through PCOS Questionnaire scale at baseline and at 6th month. Results: Sixty-five patients were enrolled and randomly assigned to Group I (n = 33) and Group II (n = 32). The menstrual cycle got regularised in 48% of Group I patients and 29% of Group II. Data were also compared to see the menstrual restoration period in both the groups. About 48% of participants in group I and 29% in group II had their menses restored after homoeopathic intervention and the difference between the groups was found to be 1.81 (p < 0.05). Improvement in menstrual cycle before and after intervention for patients in both groups showed a significant difference after the intervention (higher in Group I than Group II), confirming the efficacy of intervention in the experimental group: p < 0.05. Conclusion: This trial suggests that Ferr. met. 30C could be effective in restoring the menstrual cycle in PCOS patients. Rigorous trials and independent replications are warranted.Item Stability study of homoeopathically potentised Arsenicum album in hydrolytic amber glass class II and high-density polyethylene terephthalate over twelve months(Central Council for Research in Homoeopathy, 2024) Pietroluongo, Marcia; Giuimaraes, Thiago Frances; Fernandes, Thais de BarrosBackground: The Brazilian Homoeopathic Pharmacopoeia (BHP) recommends using glass amber Type I, II, or III as a primary container for storing homoeopathic liquid medicines. Although the glass has advantages, there are some disadvantages, such as fragility, weight, and the presence of silicate particles, which have been described as critical components involved with the generation of silicon microparticles detected in homoeopathic solutions. Objectives: The present study aimed to investigate the stability of hydroalcoholic solutions of Arsenicum album dynamised in two different vials: class II hydrolytic amber glass and amber high-density polyethylene terephthalate (PET). Materials and Methods: Two potencies of the Arsenicum album, 6C and 30C, were prepared according to BHP. The solutions were stored in glass and PET amber flasks. The stability study was carried out in a climatic chamber according to the conditions described in the Brazilian official compendium for twelve months. During the study, samples were evaluated by density, pH, refractometry, and conductivity. Microbiological purity was evaluated at the beginning and the end of stability study. Results: No statistical differences were observed in the density of samples in both conditions and packages. The pH of all samples remained around 6, and refractometry around 1.363, suggesting their chemical stability. The microbiological assays showed no pathogenic microorganisms after twelve months of storing all samples. Conclusion: The results showed that Arsenicum album 6C and 30C are stable preparations. It can also be concluded that glass bottles are suitable for storing dynamised solutions of Arsenicum album. PET bottles maintained the physicochemical and microbiological stability of the solutions and can be a potential alternative to prepare or store homoeopathic matrices. However, further studies are required to confirm the suitability of PET vials in compounding and storing homoeopathic medicines.Item Research highlights(Central Council for Research in Homoeopathy, 2024) Valentina, Annie