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Physicochemical, pharmacognostic standardisation and phytochemical analyses of the homoeopathic drug Justicia adhatoda
(Central Council for Research in Homoeopathy, 2025) Biswas, Bibaswan; Patel, Satish; Verma, Digvijay; Maity, Satyajit
Background: Justicia adhatoda (J. adhatoda), also well known as Vasaka in India is a medicinal plant chiefly used to treat respiratory ailments in traditional and alternative medical systems. Objective: This study aimed to establish the physicochemical, pharmacognostic, and phytochemical standardisation parameters of the drug. The study involved the measurement of physicochemical parameters and chemical profiling of the raw drug. The chemical characteristics of the in-house mother tincture (prepared from in-house raw drug) and commercial mother tinctures available in India were also evaluated to assess the quality of commercially available mother tinctures. Materials and Methods: The present study included pharmacognostic parameters like macroscopic, microscopic, powder studies and physicochemical parameters involving foreign matter, loss on drying, extractive values in different solvents, ash value measurements, total alkaloid content, total fixed oil and total volatile oil of the raw drug. This study also included measurement of various mother tincture parameters, such as organoleptic characteristics, specific gravity, pH, total solids, UV–Vis spectrum, high performance thin-layer chromatography (HPTLC), phytochemical screening, total alkaloid content, and chemical profiling of commercial and in-house mother tinctures to assess their comparative quality. Results: The macroscopic and microscopic studies revealed the pharmacognostic characteristics of the leaves. Low ash values indicated low metal contents. The chemical profiling and analysis indicated the presence of the same alkaloid in the raw drug and in the mother tinctures. The drug also contained several phytochemicals. Conclusion: The present study provides pharmacopoeial standards for J. adhatoda.
Homoeopathic intervention in dual autoimmune disorders: A case report on management of vitiligo and hashimoto thyroiditis
(Central Council for Research in Homoeopathy, 2025) Saklani, Nitin Kumar
Background: Vitiligo and Hashimoto Thyroiditis often occur as chronic autoimmune disorders that require careful evaluation and individualised management. This case study examines the usefulness of homoeopathic interventions in addressing the complexities of Vitiligo and Hashimoto Thyroiditis through evidence-based methodologies. Case Summary: A 57-year-old woman initially sought medical attention for a noticeable whitish discolouration on the left side of her lips. Subsequent evaluations unveiled the presence of hypothyroidism, marked by elevated Anti-TPO levels, exposing the dual autoimmune nature of her condition. The patient’s concerns centered on the aesthetic impact of vitiligo on her lips and the broader health implications of Hashimoto’s Thyroiditis. The coexistence of vitiligo and Hashimoto’s thyroiditis required simultaneous evaluation of both dermatological and thyroid-related findings. The patient underwent homoeopathic treatment at the outpatient department of the Regional Research Institute for Homoeopathy, Shimla. Following the intervention, recovery from the signs and symptoms of both vitiligo and Hashimoto’s Thyroiditis was observed. Photographic evidence and serological investigations, including Serum TSH and anti-TPO, demonstrated significant improvement in the conditions. This evidence-based case report highlights the potential positive role of Homoeopathy in the management of complex dual autoimmune conditions, providing insights into the successful recovery of the patient both clinically and serologically.
Indian Standard for Globules used in Homoeopathy
(Central Council for Research in Homoeopathy, 2025) Vivekanand, Kumar; Katarmal, Daisy; Saxena, Indra Gaurav; Taneja, Divya; Dixit, Shrishti; Manchanda, Raj Kumar
This article aims to describe and critically examine the Indian Standard (IS 18947:2024) for globules used in Homoeopathy, outlining the technical specifications, testing methods, and significance for pharmaceutical quality assurance. The implications of the standard for manufacturers, quality control laboratories, consumers and regulatory bodies engaged in the production and evaluation of homoeopathic drugs are highlighted by presenting a consolidated view of the standard’s scope and applications. This discussion underscores the continued importance of systematic standardization in ensuring the safety, consistency, and global credibility of homoeopathic medicinal products produced in India.
Strengthening Homoeopathy with Standards: The BIS initiative
(Central Council for Research in Homoeopathy, 2025) Manchanda, Raj K; Vivekanand, Kumar; Katarmal, Daisy
A workshop on systematic review and meta-analysis: CCRH's capacity building initiative for evidence synthesis
(Central Council for Research in Homoeopathy, 2025) Jain, Surbhi; Kaur, Harleen; Rani, Purnima; Singh, Gurpreet
The workshop on ‘Systematic Review and Meta-Analysis for Beginners: A Practical Introduction’ was organised by Central Council for Research in Homoeopathy (CCRH) in hybrid mode on 13th and 14th August 2025 at the auditorium of the Ayush building in New Delhi, India. The workshop with 8 technical sessions conducted over a span of 2 days, was attended by more than 400 delegates across various units/institutes of CCRH. The aim was to build capacity of scientists/ researchers of CCRH about the conduct of systematic reviews and meta- analyses, as they represent the highest level in the hierarchy of scientific evidence and are pivotal in enhancing the credibility, integration, and application of Ayush systems in mainstream healthcare.